HuberCal® Granulated Pure Calcium Carbonate

Naturally Superior

The HuberCal® granulated calcium carbonate line-up is manufactured from pure and natural limestone sources.  At Huber Health & Nutrition, as a top calcium carbonate supplier, quality is an important ingredient in all of our products.  Huber's calcium carbonate granulation manufacturing facility in Quincy, Illinois, is certified to ISO standards.  Our innovative granulated calcium carbonate portfolio goes through a rigorous and thorough screening and testing process so you are ensured consistent, high-performing products time after time. The versatility offered by these products and their properties give you flexibility in using them in your nutritional ingredient applications.

In addition to our outstanding products, we offer superior technical service support and unsurpassed customer service.  You will have the peace of mind knowing you are doing business with the J.M. Huber Corporation, one of the largest family-owned companies in the U.S.  To find the HuberCal granulated calcium carbonate product perfect for your application and to order samples of the products listed below, Contact Us or visit our Product Finder.

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Typical Properties - HuberCal® Granulated Products

HuberCal® Product Grade

Screen Analysis (U.S. mesh screens)

Suface Area BET (m²/g)

Bulk Density Loose (g/cc)

Physical Form

Calcium Carbonate

Elemental Calcium (%)

Binder System

CCG USP 100% thru 16
&#; 75% on 60
&#; 15% thru 200   <5 0.8 - 1.0 Granule HuberCal®
USP &#; 37% 50/50 Maltodextrin
/ Acacia CCG USP 100% thru 16
&#; 75% on 60
&#; 15% thru 200   <5 0.8 - 1.0 Granule HuberCal®
USP &#; 37% Maltodextrin CCG USP 100% thru 16
&#; 75% on 60
&#; 15% thru 200   <5 0.8 - 1.0 Granule HuberCal®
USP &#; 37% Acacia CCG FG 100% thru 16
&#; 75% on 60
&#; 15% thru 200   <5 0.8 - 1.0 Granule HuberCal®
FCC &#; 37% 50/50 Maltodextrin
/ Acacia CCG FG 100% thru 16
&#; 75% on 60
&#; 15% thru 200   <5 0.8 - 1.0 Granule HuberCal®
FCC &#; 37% Maltodextrin CCG FG 100% thru 16
&#; 75% on 60
&#; 15% thru 200   <5 0.8 - 1.0 Granule HuberCal®
FCC &#; 37% Acacia

HuberCal® granulated calcium carbonate products are produced and sold under license from Delavau L.L.C. and are covered by one or more of the following U.S. patents and other patents pending: 7,198,653; 7,695,528; 7,807,125; 7,850,988; 7,883,552; 8,440,236; 8,603,544; 8,609,140; 8,617,619; 8,663,706; 8,668,936; 8,697;142; 8,709,499; 8,728,173; 8,728,538; 8,741,355; 8,784,902; 8,790,713; 8,815,302; 8,821,946; 8,883,223; 8,900,642; 8,968,795; 8,993,002; and 9,333,176.

 

 

Calcium is important for skeletal structure, blood coagulation and nerve functioning. Calcium deficiencies can lead to osteoporosis. The best sources of calcium are dairy products, but for those who cannot consume these, additional calcium is needed. Calcium carbonate is the most widely used and least expensive calcium dietary supplement. As calcium is such an important supplement, it is important to manufacture calcium carbonate tablets as effectively as possible.

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Manufacturing calcium carbonate tablets, as with many other tablets, involves processing steps where powder particles adhere to each other into larger particles or granules (granulation) before being formed into the final tablet. The granulation step has many advantages, such as reducing dust, improving the flow properties of the powder mix and preventing the constituents of the mixture separating.1

Contact us to discuss your requirements of bulk calcium carbonate granulation. Our experienced sales team can help you identify the options that best suit your needs.

There are two granulation methods: wet and dry. Wet granulation involves agitating the powder, and adding a polymeric binder and liquid to bind the particles together. As the liquid is either water or a mixture of water and alcohol, a drying step is required after granulation.2 Dry granulation involves pressing the powder between a tabletting press or the rollers of a compaction or briquetting machine. Since no solvent is added to the powder, a drying step is not required, which is good for moisture- or heat-sensitive drugs,1 as well as being more environmentally friendly and economical than wet granulation. Powders with temperatures up to °C can also be compacted. However, dry granulation often produces tablets with low compactability, meaning they have low mechanical strength.3

Methods

Granule preparation. An experiment was conducted to determine whether dry granulation is suitable for producing calcium carbonate tablets. This study used precipitated calcium carbonate and four commonly used excipients: microcrystalline cellulose (Avicel PH101) (MCC), hydroxypropyl cellulose (Klucel) (HPC), maltodextrin (MD) and polyethylene glycol (PEG). All these excipients are widely known and used because of their good binding properties. Two main types of granules were used: granules of calcium carbonate prepared by roller compaction and milling, and granules containing calcium carbonate and maltodextrin prepared by wet granulation and milling.

A Miniroll (Riva SA, Argentina) system was used to compact the powder. The applied force of the rollers was 0&#; kg, and the diameter and width of the rollers was 135 mm and 26 mm, respectively. The pressure, roll and feeder speed could be varied and stored for further experiments.

The experiment used two combinations of Miniroll, pressure and roll and feeder speeds, which gave the greatest difference in tablet properties. These were picked by compacting 12 samples of calcium carbonate with no excipients added using different combinations of Miniroll settings. After being formed into tablets, their tensile strength and porosity were measured (Table 1). The pressures used ranged from 30 to 75 kg/cm2 , the feeder speeds from 18 to 40 rpm and the roll speeds from 6 to 2 rpm. The settings that gave the greatest difference in properties are highlighted in Table 1.

Table 1 Varying parameters during compaction of the different batches.

Four g batches of calcium carbonate and approximately 10% (w/w) of the four excipients were dry mixed. A fifth batch did not need mixing as it contained only calcium carbonate. The batches were compacted using the Miniroll settings given in Table 1, resulting in two samples of each batch. Details of the 10 samples are given in Table 2. The ribbons produced were milled into granules using a 1.5 mm sieve, and the granules were then separated from fines. Two different references, provided by suppliers, were used in the experiment for comparison between granules prepared by different granulation methods. Reference 1 consisted of granules of calcium carbonate prepared by roller compaction and milling. Reference 2 consisted of granules containing calcium carbonate and approximately 10% (w/w) maltodextrin prepared by wet granulation and milling.

Table 2 Samples with varying parameters and excipients during compaction.

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